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Genetic switches


Effects of macromolecular crowding on genetic switches

        M. J. Morelli, R. J. Allen and P. R. ten Wolde, 

Biophys. J. 101, 2882-2891 (2011)


DNA looping provides stability and robustness to the bacteriophage lambda switch

        M. J. Morelli, P. R. ten Wolde and R. J. Allen, 

Proc. Natl. Acad. Sci. U. S. A. 106, 8101-8106 (2009)


Statistical physics of a model binary genetic switch with linear feedback

        P. Visco, R. J. Allen and M. R. Evans, 

Phys. Rev. E 79, 031923 (2009)

          reprinted in 

Virtual Journal of Biological Physics Research


Exact solution of a model DNA-inversion genetic switch with orientational control

        P. Visco, R. J. Allen and M. R. Evans 

Phys. Rev. Lett. 101, 118104 (2008)

          reprinted in 

Virtual Journal of Biological Physics Research


Reaction co-ordinates for the flipping of genetic switches

        M. J. Morelli, S. Tanase-Nicola, R. J. Allen and P. R. ten Wolde

Biophys. J. 94, 3413 (2008)


Eliminating fast reactions in stochastic simulations of biochemical networks: a bistable genetic switch

        M. J. Morelli, R. J. Allen, S. Tanase-Nicola and P. R. ten Wolde 

J. Chem. Phys. 128, 045105 (2008).

          reprinted in 

Virtual Journal of Biological Physics Research


Sampling rare switching events in biochemical networks

        R. J. Allen, P. B. Warren and P. R. ten Wolde, 

Phys. Rev. Lett. 94, 018104 (2005).

            reprinted in 

Virtual Journal of Biological Physics Research

 

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01/11/2022

A warm welcome to our new group assistant Mr Moritz Wiegand!

30/10/2022

Congratulations to Nia Verdon who has submitted her PhD thesis!

15/10/2022

We are advertising an experimental postdoc position on biophysics of microbial aggregation in the context of the human gut microbiome. Please publicise it! Deadline is 22nd November.

01/10/2022

Check out our student Patrick Sinclair's paper in Physical Review Letters presenting a model for stochastic initiation of bacterial biofilms - and a commentary on it in Nature Reviews Physics.

30/09/2022

Congratulations to Patrick Sinclair who has successfully defended his PhD thesis!

 
 

 

 
 
 
 
 
 
 
 
 
 
 
 
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