Microbial physiology, evolution and effects of antibiotics
Lineage dynamics in growing biofilms: spatial patterns of standing vs. de novo diversity
E. Young and R. J. Allen
Frontiers in Microbiology 13 915095 (2022)
Tracking the stochastic growth of bacterial populations in microfluidic droplets
Daniel Taylor, Nia Verdon, Peter Lomax, Rosalind J Allen and Simon Titmuss
Physical Biology 19, 026003 (2022)
Stability of β-lactam antibiotics in bacterial growth media
M. Carballo-Pacheco, M. D. Nicholson, E. Lilja, R. J. Allen and B. Waclaw
PLoS Computational Biology 16, e1007930 (2020)
Predictable properties of fitness landscapes induced by adaptational tradeoffs
S. G. Das, S. O. L. Direito, B. Waclaw, R. J. Allen and J. Krug
eLife 9, e55155 (2020)
A roadblock-and-kill model explains the action of the DNA-targeting antibiotic
ciprofloxacin
N. Ojkic, E. Lilja, S. Direito, R. J. Allen and B. Waclaw
Antimicrobial Agents and Chemotherapy 64, e02487-19 (2020)
P. Sinclair, M. Carballo Pacheco* and R. J. Allen*
Physical Biology 16, 046001 (2019)
Bacterial growth: a statistical physicist's guide
R. J. Allen and B. Waclaw
Reports on Progress in Physics 82, 016601 (2019)
Predicting the dynamics of bacterial growth inhibition by ribosome-targeting antibiotics
P. Greulich*, J. Dolezal*, M. Scott, M. R. Evans and R. J. Allen (* = equal contribution)
Physical Biology 14, 6 (2017). This article is part of the special issue on antimicrobial resistance co-edited by Bartek Waclaw and me.
Antibiotic resistance: a physicist's view
R. J. Allen and B. Waclaw
Physical Biology 13 045001 (2016)
This article introduces a special issue on antimicrobial resistance co-edited by Bartek Waclaw and myself
Growth-dependent bacterial susceptibility to ribosome-targeting antibiotics
- P. Greulich*, M. Scott*, M. R. Evans and R. J. Allen
Molecular Systems Biology 11, 796 (2015) (* = equal contribution)
Lower glycolysis carries a higher flux than any biochemically possible alternative
- S. J. Court, B. Waclaw* and R. J. Allen*
Nature Communications 6, 8427 (2015) (* = equal contribution)
Mutational pathway determines whether drug gradients accelerate evolution of drug-resistant cells
- P. Greulich*, B. Waclaw* and R. J. Allen
Phys. Rev. Lett. 109, 088101 (2012) (*=equal contribution)
Selected as editor's choice and featured in a viewpoint article "Bacteria Evolve to Go Against the Grain" by Oskar Hallatschek, Physics 5, 93 (2012)
Dynamical phase transition in a model for evolution with migration
- B. Waclaw, R. J. Allen and M. R. Evans
Phys. Rev. Lett. 105, 268101 (2010)
01/11/2022
A warm welcome to our new group assistant Mr Moritz Wiegand!
30/10/2022
Congratulations to Nia Verdon who has submitted her PhD thesis!
15/10/2022
We are advertising an experimental postdoc position on biophysics of microbial aggregation in the context of the human gut microbiome. Please publicise it! Deadline is 22nd November.
01/10/2022
Check out our student Patrick Sinclair's paper in Physical Review Letters presenting a model for stochastic initiation of bacterial biofilms - and a commentary on it in Nature Reviews Physics.
30/09/2022
Congratulations to Patrick Sinclair who has successfully defended his PhD thesis!