Microbial physiology, evolution and effects of antibiotics 

Lineage dynamics in growing biofilms: spatial patterns of standing vs. de novo diversity 

E. Young and R. J. Allen

Frontiers in Microbiology 13 915095 (2022) 

 

Tracking the stochastic growth of bacterial populations in microfluidic droplets

Daniel Taylor, Nia Verdon, Peter Lomax, Rosalind J Allen and Simon Titmuss

Physical Biology 19, 026003 (2022)

 

Stability of β-lactam antibiotics in bacterial growth media

Rebecca Brouwers, Hugh Vass, Angela Dawson, Tracey Squires, Sharareh Tavaddod and Rosalind J. Allen 
 
PLoS ONE 15, e0236198 (2020)

 

Phenotypic delay: Mechanistic models and their implications for the evolution of resistance to antibiotics

M. Carballo-Pacheco, M. D. Nicholson, E. Lilja, R. J. Allen and B. Waclaw

PLoS Computational Biology 16, e1007930 (2020)

 

Predictable properties of fitness landscapes induced by adaptational tradeoffs

S. G. Das, S. O. L. Direito, B. Waclaw, R. J. Allen and J. Krug

eLife 9, e55155 (2020)

 

A roadblock-and-kill model explains the action of the DNA-targeting antibiotic
ciprofloxacin

N. Ojkic, E. Lilja, S. Direito, R. J. Allen and B. Waclaw

Antimicrobial Agents and Chemotherapy 64, e02487-19 (2020)

 

Growth-dependent drug susceptibility can prevent or enhance spatial expansion of a bacterial population

P. Sinclair, M. Carballo Pacheco* and R. J. Allen*

Physical Biology 16, 046001 (2019)

 

Bacterial growth: a statistical physicist's guide

R. J. Allen and B. Waclaw

Reports on Progress in Physics  82, 016601 (2019)

 

Predicting the dynamics of bacterial growth inhibition by ribosome-targeting antibiotics

P. Greulich*, J. Dolezal*, M. Scott, M. R. Evans and R. J. Allen (* = equal contribution)

Physical Biology 14, 6 (2017). This article is part of the special issue on antimicrobial resistance co-edited by Bartek Waclaw and me.

 

Antibiotic resistance: a physicist's view

R. J. Allen and B. Waclaw

Physical Biology 13 045001 (2016)

This article introduces a special issue on antimicrobial resistance co-edited by Bartek Waclaw and myself

 

Growth-dependent bacterial susceptibility to ribosome-targeting antibiotics

Molecular Systems Biology 11, 796 (2015) (* = equal contribution)

 

Lower glycolysis carries a higher flux than any biochemically possible alternative

Nature Communications 6, 8427 (2015) (* = equal contribution)

 

Mutational pathway determines whether drug gradients accelerate evolution of drug-resistant cells

Phys. Rev. Lett. 109, 088101 (2012) (*=equal contribution)

Selected as editor's choice and featured in a viewpoint article "Bacteria Evolve to Go Against the Grain" by Oskar Hallatschek, Physics 5, 93 (2012)

 

Dynamical phase transition in a model for evolution with migration

Phys. Rev. Lett. 105, 268101 (2010)