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Protein self-assembly


A kinetic study of ovalbumin fibril formation: the importance of fragmentation and end-joining

        J. M. D. Kalapothakis, J. Szavits-Nossan, R. J. Morris, K. Eden, S. Colvill, S. Tabor, J. Gillam, P. E. Barran, R. J. Allen and C. E. MacPhee

Biophysical Journal 108, 2300-2311 (2015)


Competition between primary nucleation and autocatalysis in amyloid fibril self-assembly

        K. Eden, R. Morris, C. E. MacPhee and R. J. Allen 

Biophysical Journal 108, 632-643 (2015).


Inherent variability in the kinetics of autocatalytic protein self-assembly

        J. Szavitz-Nossan, K. Eden, R. J. Morris, C. E. MacPhee, M. R. Evans and R. J. Allen 

Phys. Rev. Lett. 113, 098101 (2014).


Mechanistic and environmental control of the prevalence and lifetime of amyloid oligomers

        R. Morris*, K. Eden*, R. Yarwood, L. Jourdain, R. J. Allen and C. E. MacPhee 

Nature Communications 4, 1891 (2013) (* = equal contribution)

 

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01/11/2022

A warm welcome to our new group assistant Mr Moritz Wiegand!

30/10/2022

Congratulations to Nia Verdon who has submitted her PhD thesis!

15/10/2022

We are advertising an experimental postdoc position on biophysics of microbial aggregation in the context of the human gut microbiome. Please publicise it! Deadline is 22nd November.

01/10/2022

Check out our student Patrick Sinclair's paper in Physical Review Letters presenting a model for stochastic initiation of bacterial biofilms - and a commentary on it in Nature Reviews Physics.

30/09/2022

Congratulations to Patrick Sinclair who has successfully defended his PhD thesis!

 
 

 

 
 
 
 
 
 
 
 
 
 
 
 
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